Methamphetamine costs $ 100 per gram. It is used for drug addiction with a high degree of euphoria and gives a very popular effect among the young people. The methamphetamine is the N-methyl homologue of ' amphetamine , compared to amphetamine, a sympatho mimetic with increased central activity. It has limited use as a psycho stimulant, and it is subject to abuse, especially in some countries (USA, Philippines, etc.). It shares with the 'amphetamine mechanism of action, based on the synaptic release of catecholamines, particularly dopamine , the neurotransmitter deputed to stimulate the feelings of pleasure. The first use of methamphetamine has been in nasal inhalers for asthma and as a nasal decongestant. These inhalers contain levo form, however, much more active in the periphery of the right or racemic form which is used as a stimulant. At the beginning of the century the abuse of methamphetamine, especially in rural areas, has become alarming in the U.S., where it was born, namely on the west coast. Since the late '80s methamphetamine is quite present in Europe, called Speed , while in the U.S. the most common name is Meth (short for Methedrine). The drug gained notoriety because it is cheap and easy to produce: in fact, the materials used to produce it are legal and readily available. It subsequently gained a foothold in Europe, making its first appearance in London clubs, where it is called "Tick". The state where it found greater popularity in Thailand, because of the social condition of the country. Li, however, called "Ihab" 0.10 grams are enough for a single dose. This drug cannot be much found in the poorest and underdeveloped countries, because of its ability to stimulate dopamine it can be addressed, less painfully, countless hours of work, including 22 in a row, causing a total and inevitable physical exhaustion.